THE differences in life expectancy has widened between areas in Abertawe Bro Morgannwg University Health Board (ABMU) during the last ten years, according a report.
Health life expectancy in men in ABMU is around 61 years, which is significantly lower than the Welsh average of 65.
According to the Welsh Index of Multiple Deprivation, the most deprived areas are in the East Swansea.
The areas which are least deprived include Mumbles, Penrice and Gowerton.
Sharon Miller, head of primary care and partnerships, said: "Despite improving life expectancy there are considerable and increasing gaps between the most and least deprived areas.
"The life expectancy gap stands at 12 years for men and seven years for women.
"Regrettably, these gaps are amongst the worst in Wales."
In a report produced last November, it said the levels of deprivation varied considerably across the region, with pockets of high deprivation concentrated in the urban centres and the upper valleys.
The report said: "The association between deprivation and ill health is complex, but we know that lifestyle and environmental factors play a major part in the poorer health outcomes experiences by those most deprived."
Another problem that the region is struggling with is obesity in children aged four to five years is higher in the ABMU region than Wales and much higher than the rest of England.
In order to address these problems, Swansea was given with Healthy City Status by the World Health Organisation two years ago.
Its aim is to improve health for all and reduce inequalities.
Partners involved in the Healthy City programme include ABMU Health Board, City and County of Swansea, Swansea University, Swansea Council for Voluntary Services, South Wales Police and the Mid and West Wales Fire and Rescue Service.
Through its Healthy City status Swansea has also entered into a two year partnership with the Institute of Health Equity University College of London.
Ms Miller said: "This will accelerate our ability to address health inequalities.
"Another notable example of the Healthy City influence has been the establishment of Swansea University as the first 'Healthy University' in Wales, with a range of targeted work programmes being taken forward."
ABMU members will now continue to make progress on the Healthy City programme.
Find out what residents living in east and west Swansea had to say about this - in tonight's South Wales Evening PostHealth